Before sunrise on August 29, 2005, Nolan Hayes (Walker) arrives at a New Orleans hospital with his pregnant wife, Abigail (Rodriguez), who has gone into early labor. What should be one of the happiest days of Nolan';s life quickly spirals out of control when the birth goes tragically wrong and Hurricane Katrina ravages the hospital, forcing an evacuation. Nolan and his newborn baby are soon cut off from the world by power outages and rising flood waters. With his baby completely dependent on a ventilator Nolan faces one life-and-death decision after another, fighting to keep his daughter alive, as minute by agonizing minute passes...becoming unimaginable hours..